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SATB1

SATB1

SATB1

SATB1

1

patients whose tumor samples had no SATB1 expression generally had longer survival times .

那些标本中没有 SATB1 表达的患者普遍存活期更长。

2

SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci .

在染色体中，SATB1 还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。

3

SATB1 binds to BURs in double-stranded DNA by recognizing the BURs' distinctive phosphate -backbone structure .

SATB1 通过识别 BURs 的特异性磷酸骨架结构结合到双链 DNA 的该区域。

4

Moreover , by introducing SATB1 into otherwise non metastatic breast cancer cells , invasive tumors can be induced in mice ;

另外，在小鼠试验中，那些不具有侵袭性的乳腺癌细胞在导入 SATB1 之后会变成具有侵袭性的肿瘤细胞；

5

The highest levels of SATB1 were in samples from patients whose survival times had been shortest;

在来自存活期最短的患者的组织中，SATB1 的表达水平最高；

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