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p16

p16

p16

p16

2

This study did not reveal the interaction between polymorphism of GSTM1and CYP1A1 gene and methylation of P16 in lung cancer.

GSTM1 与 CYP1A1 基因多态性与 P16 基因甲基化之间未发现明显的交互作用。

3

When p16 is found in a cell, that cell is probably reaching its replication limit and grinding to a senescent halt .

一个细胞中若发现 p16Ink4a 的存在，该细胞很有可能已经到达自身复制的极限并逐渐停止继续老化。

4

The expression location of P16 protein could be a characteristic for identifying benign and malignant tissue.

P16 蛋白的表达部位对良性及恶性病变可能具有鉴别意义；

5

P16 gene involves into regulation of cell-cycle , It may be the center of cell growth differentiation control .

它参与细胞周期的调控，可能是细胞生长、分化调控的中心环节。

6

When p16 pushes a cell into senescence , the cell does not just stop multiplying. It also begins producing an odd balance of proteins.

p16 一旦让细胞衰老了，细胞就不只是停止复制而已，还会出现蛋白质不平衡的现象。

10

Objective To explore the expression and significance of E - cadherin ( ED ) and P16 gene protein in carcinoma of gallbladder .

目的探讨 E-钙粘蛋白（ED ）和 P16 基因蛋白在胆囊癌中的表达及意义。

11

Method : The Immunohistochemical method was used to analyse the expression of P16 protein in 31 specimens of TCCs of urinary bladder .

方法：采用免疫组织化学方法对 31 例膀胱移行细胞癌 P16 蛋白的表达进行分析。

12

13

The healthy cells saw their telomerase rise and p16 decrease , which would explain the boost in healthy cell growth , " Tollefsbol said. "

健康细胞中端粒酶升高，而 p16 下降，这可以解释在健康细胞对生长过程的推动作用。

15

This research will detect P16 gene and HPV16 DNA by PCR in normal skin , VIN and vulvar carcinoma to approach their relationship .

本研究采用 PCR 的方法检测外阴正常皮肤、VIN 及外阴癌中的 P16 基因和 HPV16DNA ，以探讨其间关系。

17

If you want to do some stains to distinguish ovarian high grade serous ca from endometrioid ca, P16, P53 and WT1 are good markers to choose .

如果想鉴别卵巢高级别浆液性癌与子宫内膜样癌，P16，P53 及 WT1 是不错的标记物选择。

18

To investigate the expression of p16 in pituitary adenoma .

目的探讨垂体腺瘤中 P16 蛋白的表达状况。

19

Results The methylation of p16 and DAPK gene promoter was not detected in 30 normal gastric biopsy tissues .

结果 30 例良性胃黏膜组织中没有检测到基因的异常甲基化。

20

Methods : MTS1 gene exon2 and P16 protein were detected by Mutiplex-PCR and SP immunohistochemical technique respectively.

方法：采用多重 PCR 扩增 MTS1 基因外显子 2 ，免疫组化染色（SP 法）检测 P16 蛋白表达。

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